«Մասնակից:Yeggarik/Ավազարկղ»–ի խմբագրումների տարբերություն

'''Tissue plasminogen activator''' (abbreviated '''tPA''' or '''PLAT''') is a [[protein]] involved in the breakdown of blood [[clot]]s. It is a [[serine protease]] ({{EC number|3.4.21.68}}) found on [[endothelial cell]]s, the cells that line the [[blood vessel]]s. As an [[enzyme]], it [[catalysis|catalyzes]] the conversion of [[plasminogen]] to [[plasmin]], the major enzyme responsible for clot breakdown. Human tPA has a molecular weight of ~70 kDa in the single-chain form.<ref name="tPA Human">{{cite web|url=https://www.sigmaaldrich.com/catalog/product/sigma/t5451?lang=en&region=US|title=Tissue plasminogen activator human|publisher=Sigma-Aldrich|author=|date=9 July 2017|accessdate=11 May 2018}}</ref>