«Մասնակից:Shush.hovsepyan/Ավազարկղ»–ի խմբագրումների տարբերություն
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Տող 56.
''[[LMO1]]'' գենի դուպլիկացիան նեյրոբլաստոմայով ուռուցքային բջիջների մեջ ուռուցքի ագրեսիվ տեսակի ցուցանիշ է<ref>{{cite journal | vauthors = Wang K, Diskin SJ, Zhang H, Attiyeh EF, Winter C, Hou C, Schnepp RW, Diamond M, Bosse K, Mayes PA, Glessner J, Kim C, Frackelton E, Garris M, Wang Q, Glaberson W, Chiavacci R, Nguyen L, Jagannathan J, Saeki N, Sasaki H, Grant SF, Iolascon A, Mosse YP, Cole KA, Li H, Devoto M, McGrady PW, London WB, Capasso M, Rahman N, Hakonarson H, Maris JM | display-authors = 6 | title = Integrative genomics identifies LMO1 as a neuroblastoma oncogene | journal = Nature | volume = 469 | issue = 7329 | pages = 216–20 | date = January 2011 | pmid = 21124317 | pmc = 3320515 | doi = 10.1038/nature09609 | lay-url = http://www.newswise.com/articles/new-gene-for-childhood-cancer-neuroblastoma-is-discovered | lay-source = Children's Hospital of Philadelphia | bibcode = 2011Natur.469..216W | lay-date = November 30, 2010 }}</ref>։
Նեյրոբլաստոման կապված է նաև ''NBPF10 ,'' Neuroblastoma has been linked to [[copy-number variation]] within the ''[[NBPF10]]'' gene, which results in the [[1q21.1 deletion syndrome]] or [[1q21.1 duplication syndrome]].<ref>{{cite journal | vauthors = Diskin SJ, Hou C, Glessner JT, Attiyeh EF, Laudenslager M, Bosse K, Cole K, Mossé YP, Wood A, Lynch JE, Pecor K, Diamond M, Winter C, Wang K, Kim C, Geiger EA, McGrady PW, Blakemore AI, London WB, Shaikh TH, Bradfield J, Grant SF, Li H, Devoto M, Rappaport ER, Hakonarson H, Maris JM | display-authors = 6 | title = Copy number variation at 1q21.1 associated with neuroblastoma | journal = Nature | volume = 459 | issue = 7249 | pages = 987–91 | date = June 2009 | pmid = 19536264 | pmc = 2755253 | doi = 10.1038/nature08035 | bibcode = 2009Natur.459..987D }}</ref>
Մի քանի ռիսկի գործոնները կան նկարագրված և այժմ հետազոտման առարկա են։ Due to characteristic early onset, many studies have focused on parental factors around [[fertilisation|conception]] and during [[gestation]]. Factors investigated have included occupation (i.e. exposure to chemicals in specific industries), smoking, alcohol consumption, use of medicinal drugs during pregnancy, and birth factors; however, results have been inconclusive.<ref>{{cite book |last1=Olshan |first1=Andrew F |last2=Bunin |first2=Greta R. | name-list-style = vanc |year=2000 |chapter=Epidemiology of Neuroblastoma |editor1-last=Brodeur |editor1-first=Garrett M. |editor2-first=Tadashi |editor2-last=Sawada |editor3-first=Yoshiaki |editor3-last=Tsuchida |editor4-first=P. P. A. |display-editors = 3 |editor4-last=Voûte |title=Neuroblastoma |publisher=Elsevier |location=Amsterdam |pages=33–9 |isbn=978-0-444-50222-3}}</ref>
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